文章基本信息

标题：A Review on the Foodomics Based on Liquid Chromatography Mass Spectrometry
本地全文：下载
作者：Yoshio Muguruma ; Mari Nunome ; Koichi Inoue 等
期刊名称：Chemical and Pharmaceutical Bulletin
印刷版ISSN：0009-2363
电子版ISSN：1347-5223
出版年度：2022
卷号：70
期号：1
页码：12-18
DOI：10.1248/cpb.c21-00765
语种：English
出版社：The Pharmaceutical Society of Japan
摘要：Due to the globalization of food production and distribution, the food chain has become increasingly complex, making it more difficult to evaluate unexpected food changes. Therefore, establishing sensitive, robust, and cost-effective analytical platforms to efficiently extract and analyze the food-chemicals in complex food matrices is essential, however, challenging. LC/MS-based metabolomics is the key to obtain a broad overview of human metabolism and understand novel food science. Various metabolomics approaches (e.g., targeted and/or untargeted) and sample preparation techniques in food analysis have their own advantages and limitations. Selecting an analytical platform that matches the characteristics of the analytes is important for food analysis. This review highlighted the recent trends and applications of metabolomics based on “foodomics” by LC-MS and provides the perspectives and insights into the methodology and various sample preparation techniques in food analysis.
关键词：LC-MS;foodomics;metabolomics;sample preparation;food analysis