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  • 标题:Risk Averse Model Predictive Control of Bioreactors
  • 本地全文:下载
  • 作者:Satyajeet Bhonsale ; Maurits Descamps ; Mihaela Iuliana Sbarciog
  • 期刊名称:IFAC PapersOnLine
  • 印刷版ISSN:2405-8963
  • 出版年度:2022
  • 卷号:55
  • 期号:7
  • 页码:928-933
  • DOI:10.1016/j.ifacol.2022.07.563
  • 语种:English
  • 出版社:Elsevier
  • 摘要:AbstractUncertainty is inherent in bioprocess modelling and control. Typically, uncertainties are handled using either the stochastic approach or the robust approach. Recently, the risk-averse approach, i.e., an interpolation between the stochastic and worst-case robust approach is gaining popularity. Risk-averse formulations are very useful in avoiding conservative solutions while still handling high-effect, low-probability events. In the bioreactor case considered in this paper, one such high effect low probability event is wash off caused by high feed rate or low inlet substrate concentration. A risk-averse, risk-constrained model predictive control formulation is proposed in this paper. The dynamic optimisation problem to be solved at every measurement instance is formulated using AV@R type risk objective. Similarly, probabilistic chance constraints are approximated by an AV@R-type risk constraints. The problem is then solved using the conic duality of the risk measure and an epigraphical decomposition of the nested multistage problem.
  • 关键词:Keywordsuncertaintyrisk-averse optimisationmodel predictive controlbioreactor control
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