文章基本信息

标题：Synthesis of gold nanoparticles (AuNPs) with improved anti-diabetic, antioxidant and anti-microbial activity from Physalis minima
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作者：Velmurugan Sekar ; Mysoon M. Al-Ansari ; Jayaraman Narenkumar 等
期刊名称：Journal of King Saud University - Science
印刷版ISSN：1018-3647
出版年度：2022
卷号：34
期号：6
页码：1-8
DOI：10.1016/j.jksus.2022.102197
语种：English
出版社：Elsevier
摘要：AbstractBackgroundGold nanoparticles have come to prominence among noble metals due to their characteristics. Bio-transformed nanoparticles have a low toxicity and are biocompatible and ecologically benign.Physalis minimahas been used in traditional medicine for its diuretic, laxative, and anti-inflammatory qualities since ancient times.MethodsGold nanoparticles are formed when water gold metal ions interact with an aqueous plant extract ofPhysalis minima(Au NPs).ResultsIn a UV–visible spectrophotometer, the resulting Au NPs formed a broad surface peak at 546 nm. According to the FTIR data, the peaks represent flavonoids, phenols and polyphenols meaning that flavonoids, phenols, and polyphenols were utilised as the reducing agent to create gold nanoparticles. According to the XRD pattern, the synthesised gold nanoparticles are crystalline in nature in a cubic system, with average particle sizes of roughly 36 nm. Gold nanoparticles were evaluated and found to have a zeta potential of −20.5mv, suggesting that they were stable and suitable for biological uses. The morphology of gold nanoparticles was confirmed using microscopic imaging.ConclusionThis study looked at the anti-oxidant, anti-diabetic, and antibacterial properties of gold nanoparticles (Au NPs) made fromPhysalis minima, making it exceedingly promising for biological applications.
关键词：KeywordsGold nanoparticlesPhysalis minimaAntioxidantAntidiabeticAntimicrobialBiomedical application