摘要:Introduction: As a tropical disease, malaria, which causes one death per minutes globally, is still common in both tropical and subtropical regions around the world. From millions of reported cases, one million cases would end in death each year. Data collection: Different databases and search engine, including PubMed and Google Scholar, were investigated to collect required data for the completion of the present review article by two participations authors. The following keywords were used for search in these databases Malaria in Children, Plasmodium Falciparum in Children, Malaria in Paediatrics, and Plasmodium Falciparum in Paediatrics. Results: 47 study in English was included. Children under five years old make the majority of death reports; i.e. 90% of the whole death statistics. Although malaria is mostly common in sub-Saharan Africa, it still occurs in other tropical and subtropical countries. In other regions, malaria is the result of both immigration and travel; regardless of the sources of the disease, it can be potentially severe and, sometimes, fatal. Conclusions: It would be important to become familiar with the clinical presentation of malaria among pedestrians and find approaches to prompt diagnosis, appropriate treatment and sufficient prevention methods against malaria among pedestrians.