摘要:Introduction: The increasing development of software in e-learning has opened a new horizon in education. The current research was conducted to assess the effect of web-based teaching of anatomy course on medical students’ attitude, perceived ease of use, perceived benefit and satisfaction with teaching method at Kermanshah University of Medical Sciences.Methods: The present study was an interventional quasi-experimental study that was carried out on medical students at Kermanshah University of Medical Sciences. The students were divided into two groups, one group was taught through web-based teaching method and the other one was taught via traditional teaching method. Data were collected by a researcher-made questionnaire with confirmed validity and reliability using self-report technique. The questionnaires were collected from the groups at the beginning and end of the semester. Data were analyzed by SPSS-21 software using chi-square, t-test and regression analysis and p<0.05 was considered significant.Results: The age range of the participants was 18-38 (19.82±2.06). The findings showed that 40.2% of the participants had experienced web-based learning. After intervention, the mean scores of perceived ease of use, perceived benefit, attitude and satisfaction with teaching method among the students receiving web-based teaching were significantly higher than the control group (p<0.05).Conclusion: The results of the current study indicated higher perceived ease of use and perceived benefit, more favorable attitude and higher satisfaction with the teaching method among the students taught through web-based teaching method, which might promote the quality of learning.