文章基本信息

标题：Anticoagulantes orais: aspectos farmacológicos e monitorizao terapêutica
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作者：André Pires de Oliveira Silva ; Joo Paulo Costa Lima ; Sérgio Ruas Nascimento 等
期刊名称：Research, Society and Development
电子版ISSN：2525-3409
出版年度：2022
卷号：11
期号：8
页码：1-9
DOI：10.33448/rsd-v11i8.30677
语种：English
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：Anticoagulants are highly efficient drugs, however, their use must be analyzed in terms of pharmacological aspects and therapeutic monitoring is crucial and healthy in cases of venous thromboembolism (VTE). Therefore, this study aims to address the pharmacological aspects and how therapeutic monitoring should be carried out in the use of oral anticoagulants in cases of VTE, analyzing studies on the subject. For this, a literature review was carried out, based on studies dated from 2016 to 2022, from scientific databases of studies on the subject, through a narrative literature review. Ten articles were selected. Among the results, it was seen that the ten articles highlighted in the table emphasize types of oral anticoagulants, which varied according to studies, thus achieving the objectives of the study, demonstrating that the new generation of anticoagulants works to direct a specific step of the coagulation cascade and with the possibility of replacing common pharmacological treatments, bringing greater safety and reduction of side effects. Concluding that anticoagulant therapy was based almost exclusively on the use of heparin, but that over the last few decades, more studies have been developed and new classes of anticoagulant drugs have significantly changed the therapeutic arsenal, bringing greater efficacy and safety in relation to conventional treatment within of the clinical context.
关键词：Deep Vein Thrombosis;Anticoagulants;Pharmacist professional.