文章基本信息

标题：Modelos experimentais para induo de leso muscular em roedores: uma reviso de literatura
本地全文：下载
作者：Pammela Weryka da Silva Santos ; Thalyta Cibele Passos dos Santos ; Fuad Ahmad Hazime 等
期刊名称：Research, Society and Development
电子版ISSN：2525-3409
出版年度：2022
卷号：11
期号：7
页码：1-21
DOI：10.33448/rsd-v11i7.30133
语种：English
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：Objective: the present study aims to evidence the most recurrent muscle injury techniques in the literature. Methodology: This is a bibliographical research of the integrative review type of literature. The articles were searched in 2021, from November 22 to 24, in the PubMed database, using the eligibility criteria. Results and Discussion: According to the search strategy used in this study, of all articles only 28 studies met the eligibility criteria. When analyzing the publication journals, it was observed that the most recurrent were PLoS One (7.14%), Int J Med Sci (7.14%), and J Trauma Acute Care with (7.14%). It was also evidenced that the number of publications on the subject has been growing over the years, when it compared the year 2016 (10.71%) with later years, except in 2019 with the same percentage of 10.71% and 2021 with zero publication. The breeds most used in the experiments were Sprague-Dawley (32.14%) and Wistar with 25%. There was a predominance of models due to contusion (35.71%), followed by excessive use injury (10.71%), and traumatic injury (10.71%), for induction of muscle injury in rodents. Conclusion: According to the results of this review, the most recurrent muscle injury induction models were injury by contusion, followed by excessive use injury, and traumatic injury. However, all the techniques addressed in the present study were able to reproduce with excellence the mechanism of muscle injury.
关键词：Experimental models;Animal model;Lesions and wounds;Musculoskeletal;Mice.