文章基本信息

标题：Misoprostol como acarretador abortivo na Síndrome de Moebius em pessoas de baixa renda no Brasil
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作者：Lara Isobel Vieira Bacelar ; Jucilene da Silva Sousa ; Nágila Iane Pacheco 等
期刊名称：Research, Society and Development
电子版ISSN：2525-3409
出版年度：2022
卷号：11
期号：3
页码：1-9
DOI：10.33448/rsd-v11i3.26572
语种：English
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：Introduction: Misoprostol is a prostaglandin E1 analogue with valence-restricted abortifacient properties, which is correlated with the presence of congenital abnormalities in newborns exposed in the uterus and, in Brazil, many women use inappropriate abortion methods. Objective: to establish a survey of data on Moebius syndrome in unsuccessful abortion attempts due to the use of misoprostol by low-income women. Methodology: For the preparation of this article, bibliographic research was carried out in search of articles available in the databases: Scientific Electronic, Scielo, Google Scholar, Brazilian Journal on Health Promotion, published between the years 2012 - 2021. Results and Discussions: The pharmacological action of Cytotec or Prostokos is direct on the prostaglandin receptors, acting on cervical collagen, causing changes in its physicochemical structure, and as a consequence, softening, erasing and maturation of the uterine cervix, in addition to promoting and stimulating uterine contraction. If the abortion attempt is not successful, it results in a disruptive vascular effect, causing damage to the nuclei and cells of the cranial nerves, occurring in the fourth week of pregnancy, impairing the development of limbs and organs, presenting a greater disposition to aggression and vulnerability to the manifestation of fetal malformations. Moébius Syndrome can manifest soon after birth, the child presents throughout the day a limitation when closing the eyelids and when sleeping cannot close them completely due to the abducens nerve paralysis. Conclusion: The need for greater investment in research on the proposed topic is affirmed.
关键词：Moebius Syndrome;Misoprostol;Abortion.