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标题：O índice de produtos de acumulao lipídica como bom preditor de risco cardiovascular em pacientes com doena renal crnica em hemodiálise
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作者：Alexandre Danton Viana Pinheiro ; Francisca Isabelle da Silva e Sousa ; Dayane Estéfane Barros Albuquerque Linhares 等
期刊名称：Research, Society and Development
电子版ISSN：2525-3409
出版年度：2022
卷号：11
期号：2
页码：1-10
DOI：10.33448/rsd-v11i2.25401
语种：English
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：Objective: To evaluate the predictive power of the Lipid Accumulation Products (LAP) index in the identification of cardiovascular risk in patients with kidney disease undergoing hemodialysis compared to traditional anthropometric and biochemical indicators. Methods: cross-sectional study involving 77 patients with Chronic Kidney Disease (CKD) undergoing hemodialysis treatment. Identification data, anthropometry and biochemical measurements were collected. Anthropometric, biochemical and combination of both (LAP) indicators were calculated. A receiver operating characteristic (ROC) curve was performed and the areas under the curve were estimated in order to identify the power of identification of Cardiovascular Risk (CVR) and establish cutoff points for the indicators. Results: Most individuals presented cardiovascular risk according to the Waist-Height Ratio (WHR). Medians of total cholesterol and triglycerides and mean LDL-c were higher in the CVR group assessed by non-HDL cholesterol compared to those without CVR (p<0.05). The LAP score showed significant differences between the CVR groups, with the LAP median being 77.54 (45.72-142.88), higher in the group with CVR compared to those without CVR, 43.06 (30.98- 77.06). LAP (AUC: 0.705; 95%CI: 0.589-0.821; p=0.003) was the best discriminator of RCV, where LAP cutoff point >92.21, sensitivity of 44% and specificity of 92.59% were estimated to identify the RCV. Conclusion: The LAP index showed greater power in identifying the CVR when compared to isolated anthropometric or biochemical measurements.
关键词：Kidney Disease;Dialysis;Anthropometry;Cardiovascular diseases.