文章基本信息

标题：Prevalência de achados histopatológicos de mucosa esofágica e sua correlao com Helicobacter pylori
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作者：Gabrielle Barbosa Vasconcelos de Souza ; Elomar Rezende Moura ; Yasmin Tourinho Delmondes Trindade 等
期刊名称：Research, Society and Development
电子版ISSN：2525-3409
出版年度：2022
卷号：11
期号：2
页码：1-10
DOI：10.33448/rsd-v11i2.25769
语种：English
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：Introduction: esophageal pathologies with histopathological changes can cause dyspeptic symptoms, retrosternal and epigastric pain. Objectives: to identify the prevalence of histopathological findings of the esophageal mucosa and to correlate with the bacterium Helicobacter pylori (HP). Methodology: cross-sectional, retrospective study, with 1,953 histopathological reports of the esophageal mucosa. Data analyzed by absolute and relative frequency, Pearson's Chi-Square, Mann-Whitney and Chi-Square Test with Monte-Carlo simulations. Results: 1953 reports of esophageal lesions were analyzed: female gender 982 (50.3%) and median age 44. 151 (7.7%) reports were positive for HP and of these, 41 (2.3%) had gastric atrophy. Esophagitis 1427 (73.1%), metaplasia 548 (28.1%) and Barrett's esophagus 133 (6.8%) were more prevalent. Malignancy, 5 (0.3%) reports. Of the patients with PH: esophagitis 97 (64.2%), Barrett's esophagus 17 (11.3%) and metaplasia 45 (29.8%) - statistically significant pancreatic metaplasia (p<0.001). Two (1.3%) reports showed malignancy associated with PH. Correlating HP with esophageal lesions, there was a tendency to determine a higher risk of the presence of the bacteria: Barrett's esophagus (RR: 1.68 (95%CI: 1.05-2.69), epithelial hyperplasia (RR: 2.18 (RR: 2.18) 95%CI: 1.18-4.02), glycogenic acanthosis (RR: 3.69 (95%CI: 2.08-6.54), polyps (RR: 2.17 (95%CI: 1.14-4, 16), malignancy (RR: 4.91 (95%CI: 1.66-14.52) and gastric atrophy (RR: 3.44 (95%CI: 2.02-5.84). Conclusion: Barrett's esophagus, Epithelial hyperplasia, glycogenic acanthosis, polyps, malignancy and gastric atrophy are associated with an increased risk of the presence of the bacteria.
关键词：Esophageal mucosa;Histopathology;Helicobacter pylori.