文章基本信息

标题：A ilha escondida de Reil: córtex insular e sua participao nas respostas emocionais, vícios e tomadas de decises
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作者：Filipe Augusto Azevedo Caixeta ; Annelize Florêncio Rabelo ; Bárbara Queiroz de Figueiredo 等
期刊名称：Research, Society and Development
电子版ISSN：2525-3409
出版年度：2021
卷号：10
期号：9
页码：1-10
DOI：10.33448/rsd-v10i9.18226
语种：English
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：Introduction: Supported by recent studies of human neuroimaging, the insula is re-emerging as an important area of the brain, not only in the physiological and homeostatic understanding of the body, but also in pathological contexts in clinical research, implicated in distinct cognitive, affective and regulatory functions, including interoceptive awareness, emotional responses, empathetic processes, decision making and even addictive behavior catalyst. Objective: To investigate insular functions related to emotional behaviors, addictions and decision-making, which are supported by the activation of the insular cortex. Methodology: This is a descriptive research of the integrative literature review type, which seeks evidence on the insular functions related to emotional responses, addictions and decision-making. The search was carried out using PubMed, MEDLINE, Scielo, CDSR, Google Scholar, BVS and EBSCO databases, from 2003 to 2021. Results: The study confirms the necessary role of the insular cortex in the emotional and affective response. Furthermore, the insular cortex of drug users exhibits structural changes, and the activity of the insula during decision-making correlates with the propensity to relapse to use drugs. Furthermore, functional imaging studies in humans have revealed activation of the insula after drug use and craving, and one of the most striking findings of patients with insula lesions is that it stops smoking addiction. Conclusion: The insula has a multitude of functions, which may, at first, present a somewhat confusing picture, and further studies are needed to clarify this complex hidden Isle of Reil.
关键词：Insula;Autonomic Nervous System;Von Economo cells;Physiology.