文章基本信息

标题：Segurana e eficácia da celulose bacteriana obtida a partir do melao de cana-de-aúcar no processo de cicatrizao e remodelamento tecidual: uma reviso narrativa
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作者：Lara Emanuele Santana Santos ; Rafaela de Siqueira Ferraz Carvalho ; Kelly Monteiro dos Santos 等
期刊名称：Research, Society and Development
电子版ISSN：2525-3409
出版年度：2021
卷号：10
期号：16
页码：1-16
DOI：10.33448/rsd-v10i16.22773
语种：Portuguese
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：This study aimed to analyse the safety and efficacy of bacterial cellulose (CB) produced from sugarcane molasses, through studies conducted and published by the Sugarcane Biopolymers Research Group, POLISA, Biopolymers for Health. This is a narrative review of the literature that was conducted from the collection of publications on sugarcane biopolymers, linked to POLISA, Biopolymers for Health researchers. Twenty one studies published between the years 2002 to 2020 were selected, of which 11 studies related to pre-clinical evaluation and 10 to clinical evaluation. Studies involving toxicological and biocompatibility assessments described the safety and risks related to the use of CB, while those of clinical evaluation investigated the healing process and tissue remodelling, and estimated its effectiveness as a dressing. In conclusion, CB did not prove to be cytotoxic, genotoxic or acutely toxic, showing high biocompatibility, in addition, it proved to be effective in inducing the healing process and tissue remodeling.
关键词：Biopolymers;Equipment safety;Efficacy;Wound healing.