文章基本信息

标题：Influência da adio de piperina na ao antimicrobiana do óxido de Zinco e Eugenol (OZE): OZE/PIPERINA uma nova proposta de cimento odontológico
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作者：Humbérila da Costa e Silva Melo ; José Luiz Silva Sá ; Francisca Lúcia de Lima 等
期刊名称：Research, Society and Development
电子版ISSN：2525-3409
出版年度：2021
卷号：10
期号：10
页码：1-9
DOI：10.33448/rsd-v10i10.18804
语种：Portuguese
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：Piperine is the main alkaloid amide extracted from the seeds of Piper ningrum L., has biological properties of the type: antimicrobial, anti-inflammatory, bioavailability of drugs. Zinc-Eugenol Oxide (ZOE) together, constitute the cements widely used in dentistry as a temporary dressing. This study aimed to verify the antimicrobial action of the composition from Piperine and ZOE. The agar diffusion method with well drilling was used in OZE/PIP solutions with different percentages of piperine: 4, 5, 10 and 20%. The reference strains were Staphylococcus aureus, Streptococcus mutans, Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis and Candida albicans. The concentration of piperine 4% showed the greatest inhibition halos when tested with the strains P. aeruginosa (29mm), S. aureus (26mm), E. coli (24mm). The increase in the concentration of piperine in the composition did not influence the sizes of the inhibition halos, except for S. mutans that formed a 15 mm halo in the composition with 5% piperine and Enterococcus that formed 14 mm halos with 5 and 20% piperine. The composition proved to be efficient, in its different proportions, in combating more resistant microorganisms (S. aureus), and in the most common microorganisms in the oral cavity (S. mutans, C. albicans).
关键词：Piperine;Zinc oxide and eugenol;Antimicrobial;Dentistry;Dental materials.