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标题：Utilizao da liraglutida na abordagem terapêutica medicamentosa da esteato- hepatite no alcoólica (EHNA)
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作者：Anna Camilla Ferreira Lopes Valério Pinto ; Osman Batista de Medeiros Filho ; Milena Nunes Alves de Sousa 等
期刊名称：Research, Society and Development
电子版ISSN：2525-3409
出版年度：2021
卷号：10
期号：10
页码：1-12
DOI：10.33448/rsd-v10i10.18921
语种：English
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：To evaluate the effects of liraglutide administration on NASH. Consists of a systematic review of the literature in the main virtual libraries: US National Library of Medicine National Institutes of Health (PubMed), Biblioteca Virtual de Saúde (BVS), Scientific Electronic Library Online (SCIELO) and Latin American and Caribbean Literature in Health Sciences (LILACS) in the last five years, admitting articles from clinical trials. Liraglutide is an analogue of the glacagon 1-like peptide hormone (GLP-1) that acts in suppressing appetite and de novo lipogenesis (DNL), decreasing glucagon release, increasing insulin release and sensitization, among others. For these reasons, its fronts to combat NASH range from the reduction and control of the lipid profile, to the repair of hepatocytes. Currently, with the obesogenic environment found in society, drug therapy has become a great ally of the medical community, as well as in facilitating goals for the patient. The use of liraglutide in NASH proved to be effective in slowing and resolving it, with therapies ranging from 26 to 48 weeks and doses ranging from 0,9 mg to 3,0 mg.
关键词：Non-alcoholic Fatty Liver Disease;Drug Therapy;Liraglutide.