文章基本信息

标题：The Role of OmpC and OmpF in Acidic Resistance in Escherichia coli
本地全文：下载
作者：Amany Bekhit ; Toshihiko Fukamachi ; Hiromi Saito 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2011
卷号：34
期号：3
页码：330-334
DOI：10.1248/bpb.34.330
出版社：The Pharmaceutical Society of Japan
摘要：The roles of OmpC and OmpF in acidic resistance (AR) were examined. When ompC and ompF were deleted, AR was decreased. The decreased level of AR seen in the mutant that was deficient in ompC and ompF was elevated by the addition of glutamate, but not by the addition of arginine or lysine. The expression levels of adiA and cadB were diminished by the deletion of ompC and ompF , and the conversion of arginine to agmatine and lysine to cadaverine by intact cells were reduced in the mutant. The expression of gadA / gadB was not affected by the deletion of ompC and ompF . These results suggest that the transport of arginine, lysine, and their decarboxylated products through OmpC and/or OmpF is essential for the survival of Escherichia coli cells under extremely acidic conditions.
关键词：acidic resistance;OmpC;OmpF;Escherichia coli