文章基本信息

标题：11-Tungstophosphate with Iron(II) and Hydrogen Peroxide Efficiently Detached Bacterial Biofilm
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作者：Yutaka Tajima ; Rie Takagi ; Tamiko Nakajima 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2009
卷号：32
期号：10
页码：1783-1789
DOI：10.1248/bpb.32.1783
出版社：The Pharmaceutical Society of Japan
摘要：An attempt was made to detach bacterial biofilm, formed by Staphylococcus epidermidis , by using hydrogen peroxide (H₂O₂) and tungsten compounds. When iron(II) (Fe²⁺) was mixed with undecatungstophosphate ([PW₁₁O₃₉]⁷⁻) and then H₂O₂, the resulting mixture was able to totally remove the biofilm probably because of co-generation of ¹O₂ and ·OH. A mixture of undecatungstosilicate ([SiW₁₁O₃₉]⁸⁻) and Fe²⁺ (or Cu²⁺) also gave a good result, but their catalytic activities for producing ·OH (or ¹O₂) were rather weak. An electron microscopic study showed that almost nothing was visible on the surface of a biofilm-coated glass after treatment with 1m M [PW₁₁O₃₉]⁷⁻+1 m M Fe²⁺ and 500 m M H₂O₂ (incubated for 1 h at 37 °C).
关键词：biofilm;hydrogen peroxide;reactive oxygen species;undeca(11-)tungstophosphate;undeca(11-)tungstosilicate;iron (Fe)