文章基本信息

标题：Comparison of Pathogenicity of Various Candida tropicalis Strains
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作者：Yoshio Okawa ; Masayoshi Miyauchi ; Hidemitsu Kobayashi 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2008
卷号：31
期号：8
页码：1507-1510
DOI：10.1248/bpb.31.1507
出版社：The Pharmaceutical Society of Japan
摘要：To clarify the pathogenicity and the pathogenic factors of Candida tropicalis strains, five strains, IFO 0199, IFO 0587, IFO 0589, IFO 1400, and IFO 1647, of C. tropicalis were tested for their lethality to mice, adherence to Hela cells, hydrophobicity, cell growth under acidic conditions (pH 2.0—5.9), and sucrose assimilation using C. albicans NIH A-207 strain as reference. The pathogenicity for mice of all strains was observed in the increasing order IFO 1400=IFO 0589, IFO 0587, IFO 1647=NIH A-207, and IFO 0199. The pathogenicity for mice by all the tested C. tropicalis strains was not correlated with the adherence, the hydrophobicity, or the cell growth. On the other hand, the pathogenicity correlated well with the sucrose assimilation ability. These results show that the pathogenic mechanisms of the C. tropicalis strains were different from those of the C. albicans strains.
关键词：Candida tropicalis;pathogenicity;adherence;hydrophobicity;cell growth;sucrose assimilation