文章基本信息

标题：Enzymatic Degradation of Keratin Films and Keratin Fibers Prepared from Human Hair
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作者：Chikara Yamauchi ; Wataru Okazaki ; Tadashi Yoshida 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2008
卷号：31
期号：5
页码：994-997
DOI：10.1248/bpb.31.994
出版社：The Pharmaceutical Society of Japan
摘要：Protease degradation of matrix (Ma) protein and microfibril (Mf) protein, which are the major components of human hair, were investigated. Ma or Mf protein was partially extracted from human hair and four types of keratins were prepared: Ma film, Mf film, Ma-rich fiber, and Mf-rich fiber. Of the two keratin films treated with protease, Mf film showed much higher degradation than Ma film. Of the two keratin fibers treated with protease, Mf-rich fiber showed much higher degradation than Ma-rich fiber. Protease potently degraded Mf protein. Furthermore, there was a high correlation between the extent of degradation and the water absorption of keratins.
关键词：keratin;protease;degradation;swelling;microfibril