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标题：Effectiveness of maggot extractions and secretion (E/S) of Lucilia sericata in reducing wound surface in experimental scalding burn injury
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作者：ZAHRA SADAT AMIRI ; KAMRAN AKBARZADEH ; MASOUMEH DOURAGHI 等
期刊名称：Bioteknologi
印刷版ISSN：0216-6887
出版年度：2021
卷号：13
期号：1
语种：English
出版社：UNS Solo
摘要：Amiri ZS, Akbarzadeh K, Douraghi M, Abdi KM, Afshar AA, Ghaffari J, Kordshouli RS, Akbari M, Rafinejad J2021Effectiveness of maggot extractions and secretion (E/S) of Lucilia sericata in reducing wound surface in an experimental scalding burn injuryNusantara Bioscience 13: 11-15Lucilia sericata larvae have been successfully used as medicinal larvae for wound healingThis study was performed to evaluate the therapeutic effects of the primary ointment made from excretory-secretory substances of L.sericata larvae on experimental burn wounds on rabbits under laboratory conditionsExtraction of ES from the third stage of L.sericata larvae and antibiogram testing was doneFour rabbits were randomly divided into four groups; three standard third-grade burn wounds were created on the back of each rabbit for intervention groups (B, D) of wounds were used respectively from the original ointment made from ES and ES without accompanying materialNitrofurazone ointment was used for the positive (C) and placebo ointment was used for the negative (A)On the 21st day, all scars of wounds in groups B and D were separated and the wound was free of infectious tissue, whereas in groups A and C that the scars were clinging to the baseThe level of the ulcer was significantly lower in the E/S intervention group and the infectious tissue was not observed during the treatment of group B and D woundsMethicillin-resistant Staphylococcus aureus (MRSA) did not show resistance to excretory-secretory substances of Lsericata larvaeThe debridement and recovery process was faster in the ES-treated group and the initial ointment than in the control groupThe results showed that maggot extractions and secretion (E/S) of Lsericata in reducing wound healing is appropriate for treatment.