文章基本信息

标题：Enantioselective Oxidation of Enterodiol to Enterolactone by Human Intestinal Bacteria
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作者：Jong-Sik Jin ; Nobuko Kakiuchi ; Masao Hattori 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2007
卷号：30
期号：11
页码：2204-2206
DOI：10.1248/bpb.30.2204
出版社：The Pharmaceutical Society of Japan
摘要：In the course of our experiments on the metabolic conversion of lignans to the estrogenic substances enterodiol (END) and enterolactone (ENL) by human intestinal flora, we isolated two anaerobes, Ruminococcus sp. END-1 and strain END-2, capable of oxidizing END. The former selectively converted (−)-END to (−)-ENL, while the latter selectively converted (+)-END to (+)-ENL, indicating enantioselective oxidation by intestinal bacteria.
关键词：human intestinal bacteria;oxidation;enantioselectivity;enterodiol;enterolactone