文章基本信息

标题：Change in the Respiration System of Candida albicans in the Lag and Log Growth Phase
本地全文：下载
作者：Ayako Ogasawara ; Kyoko Odahara ; Mikiko Toume 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2006
卷号：29
期号：3
页码：448-450
DOI：10.1248/bpb.29.448
出版社：The Pharmaceutical Society of Japan
摘要：The growth rate of Candida albicans at the lag growth phase was not influenced by sodium sulfite, but that at the log growth phase was remarkably inhibited. C. albicans was able to grow in aerobic conditions both with and without glucose. Under anaerobic conditions, the growth of C. albicans was completely inhibited in glucose-free RPMI1640 medium. Ethanol production was increased at the lag growth phase, but decreased at the log growth phase. When oligomycin was added to the aerobic growth condition, the growth at log growth phase was remarkably inhibited. The expression of SDH2 mRNA was low in the lag growth phase and high in the log growth phase. We concluded that C. albicans obtained ATP by fermentation at the lag growth phase, and needed oxygen to generate ATP by oxidative phosphorylation at the log growth phase.
关键词：Candida albicans;growth phase;respiration system