文章基本信息

标题：Antiallergic Activity of Aqueous Extracts and Constituents of Taxus yunnanensis
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作者：Junko Koyama ; Izumi Morita ; Norihiro Kobayashi 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2006
卷号：29
期号：11
页码：2310-2312
DOI：10.1248/bpb.29.2310
出版社：The Pharmaceutical Society of Japan
摘要：The H₂O, H₂O/MeOH (1 : 1) extracts from the wood of Taxus yunnanensis showed a remarkable inhibitory effect on induced histamine release from the human basophilic cell line, KU812. The eleven constituents purified from the wood extracts of Taxus yunnanensis were tested by an in vitro histamine release inhibition assay. Among them, secoisolarciresinol and taxiresinol were found to show inhibitory activities. A new neolignan, 2-[2-hydroxy-5-(3-hydroxypropyl)-3-methoxyphenyl]-1-(4-hydroxy-3-methoxyphenyl)propane-1,3-diol, was isolated from the wood of Taxus yunnanensis .
关键词：Taxus yunnanensis;lignan;antiallergy;neolignan;taxane-type diterpene