文章基本信息

标题：A Glycosidic Isoflavonoid from Viola hondoensis W. BECKER et H. BOISSIEU (Violaceae), and Its Effect on the Expression of Matrix Metalloproteinase-1 Caused by Ultraviolet Irradiation in Cultured Human Skin Fibroblasts
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作者：Hyung In Moon ; Joongku Lee ; Ok Pyo Zee 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2005
卷号：28
期号：6
页码：1123-1125
DOI：10.1248/bpb.28.1123
出版社：The Pharmaceutical Society of Japan
摘要：Isolation of the ethyl acetate soluble fraction from aerial parts of Viola hondoensis W. B ECKER et H. B OISSIEU yielded one major isoflavonoid glycoside, tectoridin-4′- O -β- D -glucoside. The structure of the compound was certainly determined by chemical analyses, as well as 1D- and 2D-NMR spectroscopy. The compound exhibited potent inhibitory activity against the expression of matrix metalloproteinase-1 caused by UV-irradiation in cultured human skin fibroblasts.
关键词：Viola hondoensis;tectoridin-4′-O-β- D -glucoside;matrix metalloproteinase;human skin fibroblasts