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  • 标题:Analysis and Bioactive Evaluation of the Compounds Absorbed into Blood after Oral Administration of the Extracts of Vaccinium vitis-idaea in Rat
  • 本地全文:下载
  • 作者:Xijun Wang ; Hui Sun ; Yuling Fan
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2005
  • 卷号:28
  • 期号:6
  • 页码:1106-1108
  • DOI:10.1248/bpb.28.1106
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:In order to screen the active constituents of Vaccinium vitis-idaea L., the compounds absorbed into the rat blood after oral administration of ethanol extract of the stems and leaves of V. vitis-idaea (EEV) have been analyzed. Two compounds were detected in the plasma and identified as arbutin and fraxin, which are originally existed in the crude drug. Furthermore, the pharmacological effects of the two compounds involving EEV for curing acute and chronic respiratory tract infection were tested. The results showed that both arbutin and fraxin have the anti-inflammatory, anti-coughing and phlegm-removing effects. Therefore, it was ascertained that the arbutin and fraxin would be the main active constituents of V. vitis-idaea L.
  • 关键词:Vaccinium vitis-idaea L.;arbutin;fraxin;respiratory tract infection
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