文章基本信息

标题：Suppressive Activity of the Fruit of Momordica charantia with Exercise on Blood Glucose in Type 2 Diabetic Mice
本地全文：下载
作者：Toshihiro Miura ; Yasushi Itoh ; Naoki Iwamoto 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2004
卷号：27
期号：2
页码：248-250
DOI：10.1248/bpb.27.248
出版社：The Pharmaceutical Society of Japan
摘要：The antidiabetic activity of Momordica charantia L. (Cucurbitaceae) with exercise was investigated in KK-Ay mice, an animal model with type 2 diabetes with hyperinsulinemia. The water extract of the fruit of Momordica charantia L. (MC) with exercise reduced the blood glucose of KK-Ay mice 5 weeks after oral administration ( p <0.001), and also significantly lowered the plasma insulin of KK-Ay mice under similar conditions ( p <0.01). The blood glucose of MC with exercise is lower than that of MC only or exercise only 5 weeks after the administration. MC with exercise decreased blood glucose in a glucose tolerance test. These results suggest that MC with exercise is useful for type 2 diabetic cure.
关键词：antidiabetic activity;exercise;KK-Ay;Momordica charantia;Cucurbitaceae