文章基本信息

标题：A Synthetic Retinoid Am80 (Tamibarotene) Rescues the Memory Deficit Caused by Scopolamine in a Passive Avoidance Paradigm
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作者：Koichi Shudo ; Hiroyuki Kagechika ; Noriyuki Yamazaki 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2004
卷号：27
期号：11
页码：1887-1889
DOI：10.1248/bpb.27.1887
出版社：The Pharmaceutical Society of Japan
摘要：Memory deficit in rats treated with scopolamine was rescued by several synthetic retinoids, RAR-ligands (Am80, Am555S, Tp80) and an RXR-ligand (HX630). These results may have implications for the treatment of Alzheimer's disease, age-related dementia, Parkinson's disease, and other neurological disorders.
关键词：retinoid;Alzheimer's disease;tamibarotene;dementia;RAR-ligand