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标题：Antioxidant and Free Radical Scavenging Activities of Terminalia chebula
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作者：Hua-Yew Cheng ; Ta-Chen Lin ; Kuo-Hua Yu 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2003
卷号：26
期号：9
页码：1331-1335
DOI：10.1248/bpb.26.1331
出版社：The Pharmaceutical Society of Japan
摘要：Free radicals react with biological molecules and destroy the structure of cells, which eventually causes free-radical induced disease such as cancer, renal failure, aging, etc . In this study, 6 extracts and 4 pure compounds of Terminalia chebula R ETZ . were investigated for anti-lipid peroxidation, anti-superoxide radical formation and free radical scavenging activities. The superoxide radical scavenging of the 4 pure compounds was further evaluated using electron spin resonance (ESR) spectrometry. The results showed that all tested extracts and pure compounds of T. chebula exhibited antioxidant activity at different magnitudes of potency. The antioxidant activity of each pure compound was derived from different pathways and was suggested to be specific.
关键词：Terminalia chebula;antioxidant activity;casuarinin;chebulanin;chebulinic acid;1,6-di-O-galloyl-β- D -glucose