文章基本信息

标题：In Vitro Susceptibility of Four Serotypes of Enterohaemorrhagic Escherichia coli to Antimicrobial Agents
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作者：Shigeharu Oie ; Masatada Kawakami ; Akira Kamiya 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2002
卷号：25
期号：5
页码：671-673
DOI：10.1248/bpb.25.671
出版社：The Pharmaceutical Society of Japan
摘要：We evaluated the in vitro susceptibility of four serotypes of enterohaemorrhagic Escherichia coli ( E. coli O26, E. coli O111, E. coli O157, and E. coli O165) with diverse DNA patterns to antimicrobial agents. The minimum inhibitory concentrations (MIC) determined in a total of 83 strains using Mueller–Hinton agar under aerobic and anaerobic conditions were 0.015—0.12 μg/ml for ciprofloxacin, 0.06—1 μg/ml for norfloxacin, 2—64 μg/ml for fosfomycin without glucose-6-phosphate (G-6-P), 0.25—32 μg/ml for fosfomycin with G-6-P, 2—256 μg/ml for kanamycin, 0.125—2 μg/ml for cefoperazone, and 0.06—1 μg/ml for ceftazidime. The MIC of ciprofloxacin, norfloxacin, cefoperazone, and ceftazidime were low in all strains examined.
关键词：enterohaemorrhagic Escherichia coli;susceptibility;ciprofloxacin;norfloxacin;cefoperazone;fosfomycin