文章基本信息

标题：Antipruritic Effect of Cnidii Monnieri Fructus (Fruits of Cnidium monnieri Cusson)
本地全文：下载
作者：Hideaki Matsuda ; Yasuko Ido ; Atsushi Hirata 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2002
卷号：25
期号：2
页码：260-263
DOI：10.1248/bpb.25.260
出版社：The Pharmaceutical Society of Japan
摘要：Antipruritic effects of 70% ethanol extract (CM-ext) of Cnidii Monnieri Fructus (dried fruits of Cnidium monnieri Cusson, Umberifferae) were investigated. In mice, an oral administration of CM-ext (200 and 500 mg/kg) inhibited compound 48/80-induced scratching behavior without influence on spontaneous locomotion. Isopimpinellin (3) and osthol (1), coumarin derivatives isolated from CM-ext, showed an inhibitory effect on compound 48/80-induced scratching behavior.
关键词：Cnidium monnieri;antipruritic effect;isopimpinellin;osthol