文章基本信息

标题：Determinations of Morin, Quercetin and Their Conjugate Metabolites in Serum
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作者：Su-Lan HSIU ; Chih-Wan TSAO ; Yu-Chuan TSAI 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2001
卷号：24
期号：8
页码：967-969
DOI：10.1248/bpb.24.967
出版社：The Pharmaceutical Society of Japan
摘要：Morin and quercetin are isomeric antioxidant flavonols. High-performance liquid chromatographic methods were developed for the quantitation of morin and quercetin in serum. The method employed a Cosmosil RP-18 column, using acetonitrile/0.2% o-phosphoric acid: 28/72 and 27/73 (v/v) as mobile phases, with ethyl paraben and 6,7-dimethoxycoumarin used as internal standards for morin and quercetin, respectively. Moreover, a strategy to stabilize morin/quercetin released from their glucuronides/sulfates in serum during hydrolysis was established. The present methods are applicable for determining morin, quercetin, and their glucuronides/sulfates in serum.
关键词：morin;quercetin;serum;HPLC