文章基本信息

标题：Anti-androgenic Activity of Myricae Cortex—Isolation of Active Constituents from Bark of Myrica rubra
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作者：Hideaki MATSUDA ; Miho YAMAZAKI ; Keizo MATSUO 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2001
卷号：24
期号：3
页码：259-263
DOI：10.1248/bpb.24.259
出版社：The Pharmaceutical Society of Japan
摘要：The aqueous ethanol extract of Myricae Cortex (bark of Myrica rubra SIEB. et ZUCC., Myricaceae) showed in vitro testosterone 5α-reductase inhibitory activity and in vivo anti-androgenic activity using growth of flank organ in castrated Syrian hamsters and/or hair regrowth after shaving in testosterone-treated C57Black/6CrSlc mice. Three constituents, myricanone, myricanol, and myricetin were identified as the main active principles.
关键词：Myrica rubra;testosterone 5α-reductase;anti-androgenic activity;hair regrowth