文章基本信息

标题：Rat Small Intestine Muscle Relaxation Alkaloids from Orixa japonica Leaves
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作者：Shinji FUNAYAMA ; Rioko TANAKA ; Yasuhiro KUMEKAWA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2001
卷号：24
期号：1
页码：100-102
DOI：10.1248/bpb.24.100
出版社：The Pharmaceutical Society of Japan
摘要：Two quinoline alkaloids, japonine (1) and eduline (2) were isolated from the methanol extract of the leaves of Orixa japonica as relaxants against rat small intestine muscle. The activity of these alkaloids was comparable to that of the typical muscle relaxant papaverine (4). This is also the first report of the isolation of eduline (2) from O. japonica.
关键词：Orixa japonica;quinoline alkaloid;japonine;eduline;rat small intestine;relaxant effect