文章基本信息

标题：Long Non-coding RNAs Associated with Brain Disorders: A Literature Review
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作者：Arash Abdolmaleki ; Arash Abdolmaleki ; Sevin Ferdowsi 等
期刊名称：Gene, Cell and Tissue
印刷版ISSN：2345-6841
出版年度：2021
卷号：8
期号：3
DOI：10.5812/gct.111802
语种：English
出版社：Zahedan University of Medical Sciences
摘要：Abstract Context: Neurodegenerative diseases (NDs) are neurological disorders characterized by the degeneration of the central nervous system (CNS). Studies have examined interactions between long non-coding RNAs (lncRNAs) and functioning of the CNS in NDs. In this study, we summarized the role of different lncRNAs in most NDs. Methods: In this study, different papers published between years 2003 and 2020 were reviewed. Results: LncRNAs can play a significant role in the development of brain disorders. Conclusions: The dysregulation of lncRNAs has been shown to affect NDs such as Alzheimer's disease (AD) and Parkinson’s diseases (PD). In this review, we compiled recent findings related to the main lncRNAs associated with brain disorders.
关键词：Brain Disorders;Lncrna;Neurodegenerative Diseases;Nervous System