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标题：Prediction of Blood Lactate Accumulation from Excess CO2 Output during Constant Exercise
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作者：Kohji Hirakoba ; Atsuo Maruyama ; Kohji Misaka 等
期刊名称：Journal of PHYSIOLOGICAL ANTHROPOLOGY and Applied Human Science
印刷版ISSN：1345-3475
出版年度：1996
卷号：15
期号：5
页码：205-210
DOI：10.2114/jpa.15.205
出版社：Japan Society of Physiological Anthropology
摘要：To determine the predictability of blood lactate accumulation from excess CO₂ output derived from bicarbonate buffering of lactic acid during constant exercise, eight normal active volunteers were studied during three stages of constant exercise on a cycle ergometer. Three work rates consisted of 100% (stage I), 120% (stage II) and 150% (stage III) of each subject's anaerobic threshold (AT), each of which was lasted for 4 min. Excess CO₂ output (Ex CO₂, ml) at each stage of constant exercise was estimated from the integral of difference between total VCO₂.and aerobic VCO₂ (from regression line for VCO₂ and VO₂ at exercise intensities below the AT obtained in incremental exercise test). Ex CO₂ Per body mass (Ex CO₂·mass^-1) was increased progressively with blood lactate (La) accumulation from rest to each stage of constant exercise. Mean values (± SD) in the measured La accumulation (ΔLa, _measured) and predicted La accumulation (ΔLa, _predicted) at three stages of constant exercise were 1.82 ± 0.83 vs 3.19 ± 1.70 for stage I, 5.58 ± 3.47 vs 7.09 ± 3.28 for stage II and 12.19 ± 2.36 vs 12.74 ± 1.83 mmol·l^-1 for stage III, respectively. There was a significant difference between ΔLa, _measured and ΔLa, _predicted at Stage I (p<0.05), but no significant differences between these two variables at stage II and III. The averaged difference from ΔLa, _predicted to ΔLa, _measured at stage III (0.55 rrunol·l^-1) showed a tendency to be smaller than stage I (1.38 mmol·l^-1) and II (1.50 mmol·l^-1). On the other hand, ΔLa, _predicted was found to correlate very closely with ΔLa, _measured (r=0.954, P<0.001, n=20). The results of this study suggest that the changes of La accumulation could be predicted from excess CO₂ 0utput generated in constant exercises above the AT.
关键词：aerobic CO2;bicarbonate buffering;anaerobic threshold