文章基本信息

标题：Fiber-Optic Distributed Sensing Network for Thermal Mapping of Gold Nanoparticles-Mediated Radiofrequency Ablation
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作者：Akbota Sametova ; Sabit Kurmashev ; Zhannat Ashikbayeva 等
期刊名称：Biosensors
电子版ISSN：2079-6374
出版年度：2022
卷号：12
期号：5
DOI：10.3390/bios12050352
语种：English
出版社：MDPI Publishing
摘要：In this work, we report the design of an optical fiber distributed sensing network for the 2-dimensional (2D) in situ thermal mapping of advanced methods for radiofrequency thermal ablation. The sensing system is based on six high-scattering MgO-doped optical fibers, interleaved by a scattering-level spatial multiplexing approach that allows simultaneous detection of each fiber location, in a 40 × 20 mm grid (7.8 mm 2 pixel size). Radiofrequency ablation (RFA) was performed on bovine phantom, using a pristine approach and methods mediated by agarose and gold nanoparticles in order to enhance the ablation properties. The 2D sensors allow the detection of spatiotemporal patterns, evaluating the heating properties and investigating the repeatability. We observe that agarose-based ablation yields the widest ablated area in the best-case scenario, while gold nanoparticles-mediated ablation provides the best trade-off between the ablated area (53.0–65.1 mm 2, 61.5 mm 2 mean value) and repeatability.
关键词：enradiofrequency ablationfiber-optic shape sensorsoptical fiber sensordistributed sensorsgold nanoparticlesbiomedical sensors