文章基本信息

标题：Metabolic and Nutritional Aspects in Paediatric Patients with Klinefelter Syndrome: A Narrative Review
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作者：Chiara Mameli ; Giulia Fiore ; Arianna Sangiorgio 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2022
卷号：14
期号：10
DOI：10.3390/nu14102107
语种：English
出版社：MDPI Publishing
摘要：Klinefelter syndrome is the most common sex chromosomal aneuploidy in males. It is well known that patients with this syndrome have greater mortality and morbidity compared to the general population due to cardiovascular diseases and endocrine metabolism disorders. This augmented risk is due both to hypogonadism and to the syndrome itself. Therefore, correct hormonal replacement therapy and early primary prevention are crucial to these patients. Even though different studies are available on this topic in adult patients, only a few authors have focused on the paediatric population. Thus, in this narrative review, we report the current knowledge of metabolic and nutritional aspects in children with Klinefelter syndrome.
关键词：enKlinefelter syndromechildrenbone metabolismhypogonadismbody compositiondiabetesmetabolic syndromecardiovascular riskhormonal replacement therapy