文章基本信息

标题：Transcranial magnetic stimulation parameters as neurophysiological biomarkers in Alzheimer’s disease (Review Article)
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作者：Juyoun Lee ; Ae Young Lee
期刊名称：Korean Journal of Clinical Neurophysiology
印刷版ISSN：1229-6414
出版年度：2021
卷号：23
期号：1
页码：7-16
DOI：10.14253/acn.2021.23.1.7
语种：English
出版社：KoreaMed Synapse
摘要：Transcranial magnetic stimulation (TMS) is a safe and noninvasive tool for investigating the cortical excitability of the human brain and the neurophysiological functions of GABAergic, glutamatergic, and cholinergic neural circuits. Neurophysiological biomarkers based on TMS parameters can provide information on the pathophysiology of dementia, and be used to diagnose Alzheimer’s disease and differentiate different types of dementia. This review introduces the basic principles of TMS, TMS devices and stimulating paradigms, several neurophysiological measurements, and the clinical implications of TMS for Alzheimer’s disease.
关键词：Transcranial magnetic stimulation;Alzheimer’s disease;Diagnosis;Treatment