摘要:A 25-year-old male with Down syndrome (DS) [46, XY, der (13;14), +21] underwent brain magnetic resonance imaging (MRI) due to drop attacks. He had mental retardation from childhood (IQ < 50) but no subsequent cognitive decline. Consciousness was preserved during each attack and he could walk again 5 minutes later. Brain MRI showed numerous tiny microbleeds in the lobar area (n = 349), infratentorial area (n = 59), and deep regions (n = 28) without superficial hemosiderosis or white-matter lesions (Fig. 1), which would be related to cerebral amyloid angiopathy (CAA).