文章基本信息

标题：Thymus numidicus: phenolic constituents, antibacterial, and antioxidant activities of butanolic extract
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作者：Farid Ait Kaki ; Rachid Benkiniouar ; Ahmed Touil 等
期刊名称：Environmental and Experimental Biology
印刷版ISSN：1691-8088
出版年度：2021
卷号：19
期号：2
页码：67-72
语种：English
出版社：University of Latvia
摘要：Thymus numidicus Poir. (Lamiaceae) is a native plant of northern Algeria and Tunisia. It is used in traditional medicine in Algeria to treat respiratory and digestive diseases, and as a spice in food preparations. This study aimed to characterize the chemical constituents and to evaluate antibacterial and antioxidant activities of 1-butanol (BuOH) extract of aerial parts of T. numidicus. A total of 15 phenolic compounds were identified using HPLC-TOF/MS analysis, among them eight phenolic acids, five flavonoids and a stilbenoid glycoside named polydatin, which were reported for the first time from the species. Antibacterial effects of BuOH extract were determined using the disc diffusion method against four bacteria strains, where it has displayed a weak activity against three of them. In addition, BuOH extract showed significant antioxidant activity, which was measured using 1,1-diphenyl-2-picrylhydrazyl, 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) assays for free radical scavenging activity, and cupric ion reducing antioxidant capacity assay. Our results suggest the use of T. numidicus as a natural antioxidant in food and pharmaceutical industries.
关键词：antibacterial activity;antioxidant activity;phenolic compounds;Thymus numidicus