文章基本信息

标题：In Vitro Corrosion Resistance of a Layer-by-Layer Engineered Hybrid Coating on ZK60 Magnesium Alloy
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作者：Mostafizur Rahman ; Rajkamal Balu ; Naba Kumar Dutta 等
期刊名称：Sustainability
印刷版ISSN：2071-1050
出版年度：2022
卷号：14
期号：4
页码：2459
DOI：10.3390/su14042459
语种：English
出版社：MDPI, Open Access Journal
摘要：Magnesium alloys are next generation biodegradable implants for clinical applications. However, their medical applications are currently hampered by their rapid corrosion rate in the physiological environment. To overcome such limitations, we have applied a novel layer-by-layer engineering approach of introducing anodization-induced microrough oxidized surface on ZK60 magnesium alloy, followed by surface mineralization with natural calcium apatite (hydroxyapatite, HA), and surface coating with natural protein (silk fibroin, SF); which, effectively reduces corrosion and degradation rate of ZK60 in simulated body fluid. Anodization of ZK60 improved the surface adhesion strength of HA layer; HA layer increased the surface roughness, hydrophilicity and micro-hardness, whereas decreased ionic release; SF layer decreased surface microroughness and hydrophilicity, whereas improved the stability of HA layer. The SF + HA coating on anodized ZK60 effectively decreased the in vitro weight loss (degradation) by almost six times, whereas corrosion rate by more than two orders in magnitude. Such interfacial coatings, with biocompatible SF on the outer surface, could potentially expand the application of ZK60 in the field of biomedical engineering.