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  • 标题:Genetic diversity of calpastatin gene and its association with some biochemical parameters in sheep
  • 本地全文:下载
  • 作者:Milena Bozhilova-Sakova ; Milena Bozhilova-Sakova ; Ivona Dimitrova
  • 期刊名称:Journal of BioScience and Biotechnology
  • 印刷版ISSN:1314-6238
  • 电子版ISSN:1314-6246
  • 出版年度:2021
  • 卷号:10
  • 期号:2
  • 页码:99-102
  • 语种:English
  • 出版社:Plovdiv University Press
  • 摘要:The aim of the present study was to investigate the genetic diversity of calpastatin (CAST) gene and its possible effect on some blood biochemical parameters associated with meat quality in sheep. By using the PCR-RFLP method were genotyped 117 animals from two sheep breeds – Ascanian Merino (AM) and Northeast Bulgarian Merino (NEBM). Several blood biochemical parameters were studied: ALT (alanine aminotransferase), ALP (alkaline phosphatase), AST (aspartate aminotransferase), creatinine, LDH (lactate dehydrogenase), and urea. Polymorphism in the CAST gene was found in both studied breeds. The results showed statistically significant differences between levels of AST, LDH, and urea and different genotypes in the CAST gene in Northeast Bulgarian Merino and Ascanian Merino sheep breeds.
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