文章基本信息

标题：Current Practice of High Flow through Nasal Cannula in Exacerbated COPD Patients
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作者：Andrea Bruni ; Eugenio Garofalo ; Daniela Procopio 等
期刊名称：Healthcare
电子版ISSN：2227-9032
出版年度：2022
卷号：10
期号：3
DOI：10.3390/healthcare10030536
语种：English
出版社：MDPI Publishing
摘要：Acute Exacerbation of Chronic Obstructive Pulmonary Disease is a form of severe Acute Respiratory Failure (ARF) requiring Conventional Oxygen Therapy (COT) in the case of absence of acidosis or the application of Non-Invasive Ventilation (NIV) in case of respiratory acidosis. In the last decade, High Flow through Nasal Cannula (HFNC) has been increasingly used, mainly in patients with hypoxemic ARF. However, some studies were also published in AECOPD patients, and some evidence emerged. In this review, after describing the mechanism underlying potential clinical benefits, we analyzed the possible clinical application of HFNC to AECOPD patients. In the case of respiratory acidosis, the gold-standard treatment remains NIV, supported by strong evidence in favor. However, HFNC may be considered as an alternative to NIV if the latter fails for intolerance. HFNC should also be considered and preferred to COT at NIV breaks and weaning. Finally, HFNC should also be preferred to COT as first-line oxygen treatment in AECOPD patients without respiratory acidosis.
关键词：enChronic Obstructive Pulmonary Diseaseoxygenhigh flow nasal cannulanon-invasive ventilationrespiratory therapyrespiratory insufficiencyhypercapniapositive-pressure respiration