文章基本信息

标题：Wafer-Scale LSPR Substrate: Oblique Deposition of Gold on a Patterned Sapphire Substrate
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作者：Kihyeun Kim ; Ki Joong Lee ; Na Rae Jo 等
期刊名称：Biosensors
电子版ISSN：2079-6374
出版年度：2022
卷号：12
期号：3
DOI：10.3390/bios12030158
语种：English
出版社：MDPI Publishing
摘要：Label-free detection of biomolecules using localized surface plasmon resonance (LSPR) substrates is a highly attractive method for point-of-care (POC) testing. One of the remaining challenges to developing LSPR-based POC devices is to fabricate the LSPR substrates with large-scale, reproducible, and high-throughput. Herein, a fabrication strategy for wafer-scale LSPR substrates is demonstrated using reproducible, high-throughput techniques, such as nanoimprint lithography, wet-etching, and thin film deposition. A transparent sapphire wafer, on which SiO 2-nanodot hard masks were formed via nanoimprint lithography, was anisotropically etched by a mixed solution of H 2SO 4 and H 3PO 4, resulting in a patterned sapphire substrate (PSS). An LSPR substrate was finally fabricated by oblique deposition of Au onto the PSS, which was then applied to label-free detection of the binding events of biomolecules. To the best of our knowledge, this paper is the first report on the application of the PSS used as an LSPR template by obliquely depositing a metal.
关键词：enpatterned sapphire substratelocalized surface plasmon resonanceoblique depositionnanoimprint lithographywafer-scale