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标题：Biological synthesis and characterization of Passiflora subpeltata Ortega aqueous leaf extract in silver nanoparticles and their evaluation of antibacterial, antioxidant, anti-cancer and larvicidal activities
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作者：Settu Loganathan ; Kuppusamy Selvam ; Govindaraj Padmavathi 等
期刊名称：Journal of King Saud University - Science
印刷版ISSN：1018-3647
出版年度：2022
卷号：34
期号：3
页码：1-9
DOI：10.1016/j.jksus.2022.101846
语种：English
出版社：Elsevier
摘要：AbstractPassiflora subpeltatacontain rich source of secondary metabolites and its plant materials mostly used for cancer and mosquito related problem. Therefore, in this study, green synthesis of silver nanoparticles usingPassiflora subpeltataof aqueous extract (Ps-AgNPs) as reducing and stabilizing agent. The UV–Visible spectra ofPs-AgNPs showed absorption peak at 456 nm and formation of AgNPs. XRD pattern showed the crystalline nature and SEM images displayed predominantly spherical shape of NPs. FT-IR analysis exhibition capping of AgNPs by bioactive compounds fromPs-AgNPs.Antibacterial activity inPS-AgNPs shown good activity with best ofB. cereus(27 mm) at higher dose of 75 μg/mL. Antioxidant activity was tested against DPPH, ABTS and H2O2assays and the best scavenging assay were observed in DPPH with IC50value of 108.92 μg/mL. The anti-proliferative activity in human colon cancer cell-line (HT-29) indicates that the significant result with IC50value of 33.05 μg/mL.Larvicidal activity ofPS-AgNPs showed good activity againstCx. quinquefasicatuslarvae (LC50-4.99 units and LC90-22.19units). The green synthesized NPs could be potential activity and it used in different biomedical application.
关键词：KeywordsenSilver NanoparticlesFE-SEMH2O2Colon cancerCx. quinquefasciatus