文章基本信息

标题：Methodological Aspects of Indirect Calorimetry in Patients with Sepsis—Possibilities and Limitations
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作者：Weronika Wasyluk ; Agnieszka Zwolak ; Joop Jonckheer 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2022
卷号：14
期号：5
DOI：10.3390/nu14050930
语种：English
出版社：MDPI Publishing
摘要：The aim of the review was to analyse the challenges of using indirect calorimetry in patients with sepsis, including the limitations of this method. A systematic review of the literature was carried out. The analysis concerned the methodology and presentation of research results. In most studies assessing energy expenditure, energy expenditure was expressed in kcal per day ( n = 9) and as the mean and standard deviation ( n = 7). Most authors provided a detailed measurement protocol, including measurement duration ( n = 10) and device calibration information ( n = 7). Ten papers provided information on the day of hospitalisation when the measurements were obtained, nine on patient nutrition, and twelve on the criteria for inclusion and exclusion of participants from the study. Small study group sizes and study at a single centre were among the most cited limitations. Studies assessing energy expenditure in patients with sepsis by indirect calorimetry differ in the methodology and presentation of results, and their collective analysis is difficult. A meta-analysis of the results could enable multi-site and large patient evaluation. Standardisation of protocols and presentation of all collected data would enable their meta-analysis, which would help to achieve greater knowledge about metabolism in sepsis.
关键词：ensepsisseptic shockenergy expenditureenergy demandcalorimetrymetabolismclinical nutritioncritical care