文章基本信息

标题：Development of a high-performance liquid chromatography method to assess bisphenol F levels in milk
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作者：Serena Santonicola ; Maria Carmela Ferrante ; Giampaolo Colavita 等
期刊名称：Italian Journal of Food Safety
电子版ISSN：2239-7132
出版年度：2021
卷号：10
期号：4
DOI：10.4081/ijfs.2021.9975
语种：English
出版社：PAGEPress Publications
摘要：Bisphenol F (BPF) is a bisphenol A (BPA) analogue. As an endocrine disruptor, BPF shows a similar BPA hormonal activity and greater endocrine effects. To assess BPF levels in milk a selective method based on solvent extraction with acetonitrile, solid-phase extraction (SPE), high-performance liquid chromatography with fluorescence detection (HPLC-FD) system, was developed. The method showed high recovery values (from 97.60 to 107.16%), and good detection and quantification limits (LOD=0.03 μg/L; LOQ=0.1 μg/L). To validate the analytical method, quantitative analyses of n.20 milk samples of whole milk were preliminarily carried out applying a monitoring system based on the control of different stages of pasteurized whole milk processing at a dairy company. The proposed method is simple, sensitive, and might be suitable to detect BPF residues in milk processing. At the dairy company, the occurrence of BPF levels ranging from <LOQ to 2.956 μg/L was observed. Further analyses and better knowledge about the occurrence, toxicity, and exposure levels of BPF analogue in milk, particularly for vulnerable consumer categories, are needed.
关键词：Bisphenol F; High-performance liquid chromatography method; Milk