文章基本信息

标题：The Exposome and Immune Health in Times of the COVID-19 Pandemic
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作者：Javier S. Morales ; Pedro L. Valenzuela ; Adrián Castillo-García 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2022
卷号：14
期号：1
DOI：10.3390/nu14010024
语种：English
出版社：MDPI Publishing
摘要：Growing evidence supports the importance of lifestyle and environmental exposures—collectively referred to as the ‘exposome’—for ensuring immune health. In this narrative review, we summarize and discuss the effects of the different exposome components (physical activity, body weight management, diet, sun exposure, stress, sleep and circadian rhythms, pollution, smoking, and gut microbiome) on immune function and inflammation, particularly in the context of the current coronavirus disease 2019 (COVID-19) pandemic. We highlight the potential role of ‘exposome improvements’ in the prevention—or amelioration, once established—of this disease as well as their effect on the response to vaccination. In light of the existing evidence, the promotion of a healthy exposome should be a cornerstone in the prevention and management of the COVID-19 pandemic and other eventual pandemics.
关键词：enhealthy lifestyleenvironmental exposureCOVID-19vaccinesinfectious diseases