文章基本信息

标题：Effect of prostaglandin F2 _α administration on uterine polymorphonuclear neutrophil counts in Japanese heavy draft horses
本地全文：下载
作者：Tadamasa NIIKURA ; Munkhtuul TSOGTGEREL ; Chizuru NIIKURA 等
期刊名称：Journal of Equine Science
印刷版ISSN：1340-3516
电子版ISSN：1347-7501
出版年度：2021
卷号：32
期号：4
页码：117-124
DOI：10.1294/jes.32.117
语种：English
出版社：Japanese Society of Equine Science
摘要：The objective of this study was to examine the effect of prostaglandin F2 α (dinoprost) and oxytocin administration on uterine polymorphonuclear neutrophil counts in the Japanese heavy draft mare. To compare polymorphonuclear neutrophil (PMN) counts in the endometrium, a total of 162 samples were collected from 54 estruses of 47 mares (before ovulation, day 0, and day 2) using a double-guarded cytology brush. Dinoprost (PG; 5 mg) was administered intramuscularly (i.m.) only once, on day 0, whereas oxytocin (OT; 20 U i.m.) was administered three times at 12-hr intervals starting on day 0. The plasma progesterone concentrations from days 0 to 14 were not different between the non-treatment (CON), PG treatment, and OT treatment groups. The PMN counts increased in all the groups from before administration to day 0 (CON, 0.90 to 3.55; PG, 1.20 to 8.45; and OT, 0.70 to 1.70; P=0.0014, 0.0046, and 0.0073, respectively). There was a significant decrease in PMNs from day 0 to day 2 only in the PG group (P=0.0073). The pregnancy rate was not different among the CON (12/18), PG (14/18), and OT (10/18) groups. The results of this study indicate that dinoprost can reduce uterine polymorphonuclear neutrophil counts.
关键词：dinoprost; endometritis; heavy draft horse; polymorphonuclear neutrophil