文章基本信息

标题：COMPARATIVE STUDY OF AMELIORATIVE EFFECTS OF Moringa oleifera AND Trigonella foenum-graecum AGAINST COPPER OXIDE NANOPARTICLES INDUCED TOXICITYIN GILLS AND MUSCLES OF Oreochromis mossambicus
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作者：Ghazala Kaukab ; Farhat Jabeen ; Muhammad Asad 等
期刊名称：Fresenius Environmental Bulletin
印刷版ISSN：1018-4619
出版年度：2021
卷号：30
期号：8
页码：10234-10243
语种：English
出版社：PSP Publishing
摘要：Nanotechnology has shown rapid progress in various fields which had made a remarkable change in the field of therapeutics too. Current study was de-signed to evaluate comparative remedial effects of water borne Moringa oleifera seed extract (MO-SE)and Trigonella foenum-graecum seed extract (TFG-SE) against CuO-NPs induced toxicity in Oreo-chromis mossambicus through histological and oxi-dative stress analysis. The study involved 80 fish (20-25g) randomly distributed into eight groups(10 fish/group)as negative control (NC=no-dose),posi-tive control (PC=0.12mg/l CuO-NPs)and six co-treated groups of seed extracts plus CuO-NPs. MO-SE plus CuO-NPs co-treated groups were named as G1, G2 and G3 treated with MO-SE @ 32,48 and 96mg/l along with 0.12mg/l of CuO-NPs, respec-tively. Whereas, TFG-SE plus CuO-NPs co-treated groups were designated as G4, G5 and G6 treated with TFG-SE @18,26 and 52 mg/l along with 0.12mg/l CuO-NPs, respectively. In this study, sig-nificant remedial effects(p<0.05)were found in G2, G3 and G6 groups with respect to antioxidant en-zymes (reduced Glutathione, Lipid peroxidase, Malondialdehyde and Catalase) and histological analysis of gills and muscles. It was revealed that MO-SE was a strong healer compared to the TFG-SE. In this study it was concluded that MO-SE was better to ameliorate toxic effects of CuO-NPs in O. mossambicus as compared to TGF-SE and is the first to investigate the comparative ameliorative effects of both Moringa oleifera and Trigonella foenum-grae-cum seed extract against CuO-NPs in fish.
关键词：Moringa oleifera seed extract;Trigonella foenum-grae-cum seed extract;Oreochromis mossambicus;oxidative stress enzymes;Histology