摘要:Transportation and living conditions are part of horse mode of life, but are itself a stressor often re- sulting in a reduction in feed intake, body weight gain, and nutrient digestibility. Something more stress factors induces physiological, behavioural. immunological and biochemical changes that di- rectly affect health and well-being. For this reason the aim of this study was to evaluate some haemato- logical, biochemical and hormonal changes, may able used successfully to identify the impact ofmodeof live on hospitalized horses suffering from degen- erative joint disease (DJD) after consumation of herbal tea. Six animals were transported by road for approximate 1 h and accommodated in the Equine Veterinary Hospital of Trakia University, Stara Zag- ora, Bulgaria. The natural herbal tea (Herbacon GmbH, Berlin, Germany) was administered to three horses by water for drink in dose 10g/100 kg body weight together with standard therapy for osteoar- thritis during 2 months. The results of this study con- firmed that a linkage between stress and hormons and acute phase responce (APR) exists. In both groups horses Fib increased significantly after road transport and 24 and 48 h ofaccomadation compared to the previous data points. At the end of the period acute phase proteins, cortisol were insignificantly (P > 0.05) lower in treatmed group (Fb=3.69+0.15: Cortisol=0.93+0.16) with herbal tea in compare with control group (Fb=5.57±0.89: Cortisol=1.07±0.41). Based on the results presented above and consider- ing changes in studied blood parameters which are useful indicators of animal health and welfare, wecan recommend the daily use of natural herbal tea.